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SRT 1720
CAS No. 925434-55-5
SRT 1720 ( SRT-1720;SRT1720 )
Catalog No. M16631 CAS No. 925434-55-5
A potent, selective SIRT1 activator with EC1.5 of 0.16 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
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| 5MG | 48 | In Stock |
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| 10MG | 76 | In Stock |
|
| 25MG | 151 | In Stock |
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| 50MG | 290 | In Stock |
|
| 100MG | 412 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSRT 1720
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective SIRT1 activator with EC1.5 of 0.16 uM.
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DescriptionA potent, selective SIRT1 activator with EC1.5 of 0.16 uM; displays good selectivity for activation of SIRT1 versus SIRT2 (EC1.5=37 uM) and SIRT3 (EC1.5>300 uM); 1,000-fold more potent than resveratrol; improve insulin sensitivity, lower plasma glucose, and increase mitochondrial capacity in obese mice model.
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SynonymsSRT-1720;SRT1720
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSIRT1;SIRT2
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Research AreaMetabolic Disease
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Indication——
Chemical Information
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CAS Number925434-55-5
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Formula Weight469.56
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Molecular FormulaC25H23N7OS
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5
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Chemical Name2-Quinoxalinecarboxamide, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Milne JC, et al. Nature. 2007 Nov 29;450(7170):712-6.
2. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51.
3. Funk JA, et al. J Pharmacol Exp Ther. 2010 May;333(2):593-601.
2. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51.
3. Funk JA, et al. J Pharmacol Exp Ther. 2010 May;333(2):593-601.
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